Elevated LDL

Elevated LDL with Established Cardiovascular Disease

The purpose of this clinical trial is to establish if the investigational study drug can help prevent cardiovascular events, such as heart attacks, strokes, and cardiovascular-related deaths, in adults who already have been diagnosed with cardiovascular disease.

• This clinical trial is for patients with a history of cardiac disease.
• Patients who qualify for the trial should already be on a cholesterol lowering statin treatment such as Lipitor® or Crestor®.
• During the clinical trial, in addition to taking currently prescribed statin drug, patients will receive the investigational study drug or a placebo.
• The clinical trial seeks to understand the long-term health benefits of adding the investigational study drug vs. a placebo, when used in combination with a statin with or without ezetimibe drug.
• Patients will be able to stay with their primary physician.

The study drug is being researched to determine if it can lower LDL-cholesterol (also known as “bad” cholesterol).  The investigational study drug will be given as an initial dose, followed by a dose at 3 months and then every 6 months in addition to approved statin (cholesterol lowering) medication. This trial will help us understand if the investigational study drug will also reduce cardiovascular events from occurring.